Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 21, Issue 4, 2019; Page No.(837-839)

ANTITHYROID DRUG-INDUCED AGRANULOCYTOSIS, A CASE REPORT

FEMMY NURUL AKBAR AND HARI HENDARTO

Abstract

Hyperthyroidism is a common problem in general internal medicine practice. Current treatments of hyperthyroidism involve antithyroid drugs (ATD) medications. Agranulocytosis is a rare adverse effect of ATD, usually occurs within the first 23 months of treatment. However, serious life-threatening adverse effects may occur, mainly due to severe systemic infection if appropriate medical intervention is not given immediately. In this case report, a 29-year-old female, developed agranulocytosis following the treatment for thyrotoxicosis. The present case report aims to increase the awareness of the adverse effect of ATD treatment and warns that ATD should be used with caution.

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