Ecology, Environment and Conservation Paper

Vol 25, Issue 4 2019; Page No.(1911-1916)

EFFECT OF SODIUM ARSENATE ADMINISTRATION ON THE STATUS OF CELLULAR ANTIOXIDANT ENZYME ACTIVITY AND CARBOHYDRATE METABOLISM IN ISOLATED ENTEROCYTES OF MUS MUSCULUS

Salmataj S.A., Shobha U. Kamath, Surekha Bhat and Shreedhar Pai

Abstract

Consumption of arsenic-contaminated drinking water is the major cause of arsenic toxicity. Early clinical features are associated with the gastrointestinal system and include colicky abdominal pain and profuse watery diarrhoea. The effect of arsenic administration on antioxidant defense system and carbohydrate metabolism was studied in the enterocytes of Swiss albino male mice administered single dose of sodium arsenate (ARS) through oral gavage for a period of 30 days at doses of 1mg/Kg body weight and 3mg/Kg body weight. Doses were calculated based on LD50 values. Arsenate administration caused a significant dose dependent increase in MDA level and catalase activity and decrease in SOD and GST activities indicating increased oxidative stress. A significant increase in LDH activity, decrease in SDH and ATPase activity indicated decreased production and availability of ATP in enterocytes. Further research is needed to elucidate a mechanism linking these changes to the immediate gastrointestinal symptoms of arsenic toxicity.

Enter your contact information below to receive full paper.
Your Name :
Email:
Phone:
City:
Cost of Full Paper: Rs.75 for Indian Nationals or $20 (USD) for international subscribers.
By clicking on Request Paper you Agree to pay the above mentioned cost per paper.
  
Journal Issues
Vol 25, Issue 4 2019
Vol 25, Issue 3 2019
Vol 25, Nov Suppl. Issue, 2019
Vol 25, Sept Suppl. Issue, 2019
Vol 25, Aug Suppl. Issue, 2019
Vol 25, July Suppl. Issue, 2019
Vol 25, Issue 2 2019
Vol 25, May Suppl. Issue, 2019
Vol 25, April Suppl. Issue, 2019
Vol 25, Issue 1 2019
Vol 24, Issue 4 2018
Vol 24, Issue 3 2018
Vol 24, Issue 2 2018
Vol 24, Issue 1 2018
Vol 24, March Suppl. Issue 2018
Vol 24, Feb. Suppl. Issue 2018
Vol 23, Issue 4, 2017
Vol 23, Nov. Suppl. Issue 2017
Vol 23, Sept. Suppl. Issue 2017
Vol 23, Issue 2, 2017
Vol 23, Issue 3, 2017
Vol 23, Issue 1, 2017
Vol 23, Feb 2017 Suppl. Issue
Vol 22, Dec 2016 Suppl. Issue
Vol 22, Issue 4, 2016
Vol 22, Sept. Suppl. Issue , 2016
Vol 22, Issue 3, 2016
Vol. 22, June Suppl. Issue 2016
Vol 22, Issue 2, 2016
Vol. 22, April Suppl. Issue 2016
Vol 22, Issue 1, 2016
Vol 21, Issue 4, 2015
Vol. 21 Dec. 2015 Suppl. Issue
Vol. 21 Nov. 2015 Suppl. Issue
Vol 21, Issue 3, 2015
Vol 21, Issue 2, 2015
Vol. 21 Suppl.Issue August 2015
Vol 21.Suppl.Issue June 2015
Vol 21, Issue 1, 2015
Supplement Issue, Dec. 2014
Special Issue-2014
Vol 20, Issue 4, 2014
Vol 20, Issue 3, 2014
Vol 20, Issue 2, 2014
Vol. 20 Issue 01, 2014
Vol. 19 Issue 04, 2013
Vol. 19 Issue 03, 2013
Vol. 19, Issue 02, 2013
Vol. 19, Issue 01, 2013
Vol.18, Issue 04, 2012
Vol.18, Issue 3, 2012
Vol.18, Issue 2, 2012
Vol.18, Issue 1, 2012
Vol.17, Issue 4, 2011
Vol.17, Issue 3, 2011
Vol.17, Issue 2, 2011
Vol.17, Issue 1, 2011
Vol.16, Issue 4, 2010
Vol.16, Issue 3, 2010
Vol.16, Issue 2, 2010
Vol.16, Issue 1, 2010
Vol.15, Issue 04, 2009
Vol.15, Issue 03, 2009
Vol.15, Issue 02, 2009
Vol.15, Issue 1, 2009
Vol.14, Issue 04, 2008
Vol.14, Issue 2-3, 2008
Vol.14, Issue 2-3, 2008
Vol.14, Issue 1, 2008
Vol.14, Issue 2-3, 2008
Vol.13, Issue 04, 2007
Vol.13, Issue 2, 2007
Vol.13, Issue 1, 2007
Vol.12, Issue 4, 2006
Vol.12, Issue 3, 2006
Vol.12, Issue 2, 2006
Vol.12, Issue 1, 2006
Vol.12, Issue 01, 2006
Vol.11, Issue 3,4, 2005
Vol.11, Issue 2, 2005
Vol.11, Issue 1, 2005
Vol.10, Issue 04, 2004
Vol.10, Issue 03, 2004
Vol.10, Issue 02, 2004
Vol.10, Issue 01, 2004
Vol.09, Issue 04, 2003
Vol.09, Issue 03, 2003
Vol.09, Issue 02, 2003
Vol.08, Issue 04, 2002
Vol.08, Issue 03, 2002
Vol.08, Issue 01, 2002
Vol.07, Issue 04, 2001
Vol.07, Issue 03, 2001
Vol.07, Issue 02, 2001
Vol.07, Issue 01, 2001
Vol.06, Issue 04, 2000
Vol.06, Issue 03, 2000
Vol.06, Issue 02, 2000
Vol.06, Issue 01, 2000
Vol.05, Issue 04, 1999
Vol.05, Issue 03, 1999
Vol.05, Issue 02, 1999
Vol.05, Issue 01, 1999
Vol.04, Issue 1,2, 1998
Vol.03, Issue 3,4, 1997
Vol.03, Issue 01, 1997
Vol.02, Issue 1,2, 1996
Vol.01, Issue 14, 1995
Looking for Past Issues? Click here to get them!!