EFFECT OF SODIUM FLUORIDE TOXICITY ON REPRODUCTIVE ORGANS OF MALE ALBINO RATSR.K. PANDE AND SMITA TIWARI
Fluorosis is a dreaded disease caused due to high fluoride (>1.5ppm) in drinking water. In the present study fertility impact of male albino rats (Rattus rattus), weighing between 150-200 g, were kept on sodium fluoride treated water (5, 20, 50) mg/kg. b.w. for 60-90days. The results revealed that the fluoride water exposure to male rats when after rest period of 30 days90 days. The treated male rats cocaged with normal female rats caused irregular estrus cycle, reduced fertility rate, number of litters, weights of reproductive organs (Testes, Epididymis, Vas deferens, Seminal vesicle and Prostate). The data suggests that the sodium fluoride water exposure for 60-90 days caused adverse effect on reproductive organs, leading to reduced fertility and number of litters in new generations.
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